华侨大学，分子药物学研究院，福建省闽江学者特聘教授，2010

郑州大学，化学系，教授，2008

郑州大学，化学系，副教授，2002

里斯本新大学，化学生物技术研究院，FCT 博士后，2000.9---2006.8

联系方式:

崔秀灵教授

厦门市集美大道668号华侨大学分子药物学研究院，泛华大楼906

电话：0086-592-6162996，18959266696

Email: cuixl@hqu.edu.cn

研究方向:

有机合成方法学

靶向药物合成

天然产物分离与结构修饰

授课:

有机化学；有机化学基础实验；专业英语

项目：

1. 手性氮杂二茂铁环番的合成及其应用研究, 国家自然科学资金20972139

2. 基于过渡金属催化C-H键活化合成1,2-二取代二茂铁衍生物的研究21102133

3. 福建省闽江学者支持计划，福建省

4. 手性胺配体的设计合成及其在药物合成方面的应用研究，厦门科技局

List of Selected Recent Publications

1. Palladium-Catalyzed Alkenylation of Quinoline-N-oxides via C-H Activation under External-Oxidant-Free Conditions，Junliang Wu, Xiuling Cui,* Lianmei Chen, Guojie Jiang, Yangjie Wu* J. Am. Chem. Soc,2009, 13888-13889

2. Palladium Catalyzed Synthesis of Highly Substituted Naphthalenes via Direct Ring Construction from Amides with Alkynes，Junliang Wu, Xiuling Cui,* Xia Mi, Ying Li, Yangjie Wu*, Chem. Comm. 2010, 6771-6773.

3. Cyclopalladated ferrocenylimine as efficient catalyst for synthesis of arylboronate esters, Lianhui Wang, Jingya Li, Xiuling Cui *,Yusheng Wu, Zhiwu Zhu, and Yangjie Wu*, Adv. Syn. & Cat. 2010, 2002-2010

4. Synthesis of Biaryls via “One-pot” Tandem Borylation/Suzuki-Miyaura Cross Coupling Catalyzed by Palladacycle, Lianhui Wang, Xiuling Cui*, Jingya Li, Yusheng Wu, Zhiwu Zhu, and Yangjie Wu* Euro. J Org. Chem. 2012 595-603.

5. Facile synthesis of aryl(het)cyclopropane catalyzed by palladacycle, Min Zhang, Xiuling Cui*, Xiaopei Chen, Lianhui Wang, Jingya Li, Yusheng Wu, Lifen Hou and Yangjie Wu*, Tetrahedron, 2012 900-905.

6. Synthesis and Structure of Heteroannular Cyclopalladated Chiral Ferrocenylimines. Theoretical Interpretation of the Cyclopalladated Complexes Based on Density Functional Calculations Hengyu Qian, Xiuling Cui*, Mingsheng Tang, Chun Hui, Cheng Liu, Yangjie Wu*, New J. Chem 2009，33， 668-674

7. Syntheses, structures of N-(substituted)-2-aza-[3]-ferrocenophanes and their application as redox sensor for Cu²⁺ ion，Lianmei Chen, Xiuling Cui*, Haitao Cheng, Maoping Song, Mingsheng Tang, Donghui Wei, Yangjie Wu*，Applied Organomet Chem, 2012, Accepted

8. Rigid Ferrocenophane and its Metal Complexes with Transition and Alkaline-earth Metal Ions, Xiuling Cui, Rita Delgado, J. Costa, Michael G. B. Drew, Paulo J. Costa and Vítor Félix, Polyhedron, 2010，1696-1705。

9. Study on Heck Reaction Promoted by Carbene Adduct of Cyclopalladated Ferrocenylimine and the Related Reaction Mechanism，Gerui Ren, Xiuling Cui, Erbing Yang, Fan Yang and Yangjie Wu*，Tetrahedron, 2010, 4022-4027.

10. Efficient Synthesis of Biaryls through Kumada Reaction Catalyzed by Carbene Adducts of Cyclopalladated Ferrocenylimine, Gerui Ren, Xiuling Cui, Yangjie Wu*, Euro. J. Org. Chem. 2010, 2372-2378

11. 天然药物抗HBV作用机制的研究进展，李沿涛, 许瑞安, 崔秀灵*，中国药理学与毒理学杂志， 2012 Accepted

12. 基于钯催化C-H键活化的多米诺反应, 沈金海，程国林，崔秀灵*, 化学进展， 2012 Accepted

13 Carbene Adduct Of Cyclopalladated Ferrocenylimine Catalyzed α-Arylation Of Ketones With Aryl Chlorides Or Bromides, Jinli Zhang, Xueqian Yang, Xiuling Cui, Yangjie Wu* Tetrahedron, 2011 8800-8807.